ANR tackles opioid dependence by examining the core biological processes and neuropharmacology relative to standard brain activity, and it assesses the standard interactions that existed prior to modifications caused by opioid exposure in the nervous system. Individuals developing an opioid dependence from outside opioids reduce their natural endorphin synthesis and simultaneously cause the nervous system to increase the number of operational endorphin/opioid receptors. As misuse escalates, this forms a harmful self-sustaining loop. As additional receptors are generated, greater quantities of opioids or narcotics become necessary to meet the body's neuro-biochemical requirements.
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ANR deals with opioid dependence through the lens of fundamental biological changes and brain chemistry compared to normal neural function, exploring the standard relationships that precede adaptations from opioid interaction with the nervous system. People who form an opioid dependence from external opioids diminish their innate endorphin output and at the same time stimulate the nervous system to elevate the count of active endorphin/opioid receptors. With ongoing and excessive use, this evolves into a detrimental repeating cycle. As more receptors are created, the person demands increasingly higher amounts of opioids or narcotics to address their biochemical necessities.
